THE BURDEN OF NEOPLASTIC DISEASES AND TRENDS OF NEOPLASTIC MORTALITY IN NIGERIA: A TERTIARY HEALTH CENTER PERSPECTIVE IN SOUTH-EASTERN NIGERIA.
Formerly Published in Vol. 10 No. 1 Jan. - Jun., 2024
DOI:
https://doi.org/10.83120/pmj.vol4no1.27Keywords:
Pattern of death, Mortality, policy, cancer, neoplastic diseases, neoplastic deathsAbstract
Background: Morbidity and Mortality analysis in relation to neoplastic diseases is an exposition on the pattern, trends and frequencies of neoplastic deaths. This knowledge is relevant to public health planning, essential health needs, assessing intervention programs, and re-evaluation of health policies in any organized society both in developed and developing countries worldwide.
Aims: To determine the burden and the frequency of neoplastic deaths in David Umahi Federal University Teaching Hospital, Uburu.
Objectives: To determine social demography of neoplastic deaths in DUFUTH and the frequency of mortality and the burden due to Neoplastic diseases in David Umahi Federal University Teaching hospital between 2022 to 2025.
Result: Death due to neoplasm accounted for 19% (54) out of 291 mortalities within the study period. Prostatic carcinoma was the highest cause of death which accounted for 33.3%. Breast cancer followed this trend with 20.5% (11 deaths) occurrence. Liver cancer is third most common cause of cancer deaths accounting for 11.2% (6 deaths) while this was closely followed by intracranial meningioma (WHO grade 2) 7.5%(4 deaths). Cases of Leiomyosarcoma, Fibrosarcoma of the spine, gastric cancer, colon cancer, lymphoproliferative disorder, bronchogenic carcinoma, metastatic Fibrosarcoma, all stood at 1.8%(1 deaths) respectively. Osteosarcoma, Cervical cancer, Nasopharyngeal carcinoma and endometrial cancer took a frequency of 3.7%(2 deaths) per case respectively.
Conclusion: Prevention and effective treatment remain the only feasible approach to reverse the global increase in neoplastic death and its negative impact on our fragile health facilities across the country. Although no cancer is more bothersome than the other, there is urgent need to improve screening, prevention and effective treatment methods for prostatic cancers in males and breast cancers in females due to their rising incidence and their devastating effects on the affected patients and family cannot be overemphasized. Although some cancer cases may be inevitable, government can establish policies that can reduce population-level exposure to recognized cancer risk factors, including smoking, overweight, obesity, and infections
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References
1. Christopher Chinedu Obiorah, Cause specific and trends of mortality in Nigeria: A six year study of a tertiary hospital; International Journal of Medicine and Medical Sciences. Vol. 12, pp. 1-7, January-June 2020
2. Fadelu, T., Rebbeck, T.R. The rising burden of cancer in low– and middle–Human Development Index countries. Cancer. 2021; 127: 2864-2866.
3. Okoroiwu HU, Uchendu KI, Essien RA (2020) Causes of morbidity and mortality among patients admitted in a tertiary hospital in southern Nigeria: A 6 year evaluation. PLoSONE 15: e0237313.
4. C. C. Nwafor Chukwuemeka Charles, M. A. Nnoli Mar n Azodo1, C. AbaliChuku; Causes and pattern of death in a tertiary hospital in south eastern Nigeria. Sahel Medical Journal. VOL. 17 Issue 3 July-September 2014.
5. Brown KF, Rumgay H, Dunlop C, Ryan M, Quartly F, Cox A, Deas A, Elliss-Brookes L, Gavin A, Hounsome L, Huws D. The fraction of cancer attributable to modifiable risk factors in England, Wales, Scotland, Northern Ireland, and the United Kingdom in 2015. British journal of cancer. 2018; 118: 1130-41.
6. Obiora Jude Uchendu. Cancer Incidence in Nigeria: A Tertiary Hospital Experience. Asian Pac J Cancer Care, 2020. 5, 27-32
7. Cecchini M, Devaux M, Sassi F. Assessing the impacts of alcohol policies: A microsimulation approach. OECD Health Working paper 80. 2015.
8. Bray F, Laversanne M, Weiderpass E, Soerjomataram I. The ever-increasing importance of cancer as a leading cause of premature death worldwide. Cancer. 2021; 127:3029-3030.
9. Available at https://www.afro.who. int/health-topics/ noncommunicable-diseases WHO. Non communicable Diseases. 2024. Accessed November 6, 2024.
10. Ferlay J, Laversanne M, Ervik M, et al. Global Cancer Observatory: Cancer Tomorrow. International Agency for Research on Cancer. Accessed November 6, 2024.
11. Torre LA, Siegel RL, Ward EM, Jemal A. Global cancer incidence and mortality rates and trends—an update. Cancer epidemiology, biomarkers & prevention. 2016 Jan 1;25:16-27
12. . Omosun A, Abayomi A, Ogboye O,Lajide D,Oladele D,Popoola A, Banjo AA, Chugani B, Mabadeje B, Abdur-Razaak H, Wellington O, Andu L, Adepase A, Adesina F, Olonire O, Fetuga A, Onasanya O, Awosika F, Folarin-Williams O, Anya SE. Distribution of Cancer and Cancer Screening and Treatment Services in Lagos: A 10-Year Review of Hospital Records. JCO Glob Oncol. 2022; 8: e2200107.
13. Felix E. Ehidiamhen1,2*, Godson O. Eze3, Stanley E. Ogbata1,2, Cornelius C. Chukwuegbo1, Lateef A. Odukoya4, Andrew I. Okoawoh5, Doubra O. Owolabi6, Robinson U. Ugwuanyi7, Olushola O. Jegede1, Chinedu N. Idakari8, Martins A. Nnoli9, Modupeola O. Samaila10: Comparative Analysis of Ki-67 Protein as a Proliferative Expression Index in Cutaneous Basal and Squamous Cell Carcinoma in Federal Medical Centre Umuahia, Nigeria, Open Journal of Pathology, 2024, 14, 91-106
14. Shah SC, Kayamba V, Peek RM Jr, Heimburger D. Cancer Control in Low- and Middle-Income Countries: Is It Time to Consider Screening? J Glob Oncol. 2019; 5:1-8. doi:10.1200/JGO.18.00200
15. WHO Guide to cancer early diagnosis. 2024. Accessed November 6, 2024. https://www.who.int/cancer/ publications/cancer_early_diagnosis/en
16. Stefania Boccia, Carlo La Vecchia and Paolo Boffetta. Epidemiology of Cancer and Principles of Prevention. Springer International Publishing Switzerland 2015 S. Boccia et al. (eds.), A Systematic Review of Key Issues in Public Health, Chapter · March 2015 DOI: 10.1007/978-3-319-13620-2_5
17. Sagan A, McDaid D, Rajan S, Farrington J, McKee M. Screening: When is it appropriate and how can we get it right? Copenhagen (Denmark): European Observatory on Health Systems and Policies; 2020
18. Cheatley J, Aldea A, Lerouge A, Devaux M, Vuik S, Cecchini M. Tackling the cancer burden: the economic impact of primary prevention policies. Molecular Oncology. 2020; 15779-789
19. 19. Anna Lewandowska1, Rafał Filip2. Knowledge on neoplastic diseases among young rural inhabitants: Annals of Agricultural and Environmental Medicine 2017, Vol 24, No 3, 496–501
20. 20. Gulmira Umarova*, Аrstan Mamyrbayev, Saule Bermagambetova, Akmaral Baspakova, Umyt Satybaldieva, Valentina Sabyrakhmetova, Talgar Abilov, Gulnar Sultanova, Raisa Uraz. Morbidity, Disability and Death Rates of The Population Due to Malignant Neoplasms in Uralsk City in The Republic of Kazakhstan. Asian Pac J Cancer Prev, 17, 5159-5164
21. Jialiu Fang1· Xiaoyue Zhang2· Rui Zhu3· Xing Xing4· Ziyuan Shen2· Jisen Zhang1· Guoqi Cai2,5. Global trends and projections in the burden of malignant neoplasm of bone and articular cartilage. Discover Public Health (2025) 22:110 | 22.
Zachorowalność wśród dzieci i młodzieży na wybrane choroby nowotworowe w województwie śląskim. The incidence of selected neoplastic diseases among children and adolescents in the Silesian Voivodeship. PRACE EMPIRYCZNE I DONIESIENIA Z BADAŃ EMPIRICAL STUDIES AND RESEARCH REPORTS. Sztuka Leczenia 2023, tom 38, nr 1, ss. 15–22 https://doi.org/10.4467/18982026SZL.23.002.17916.
22. 23. Paulina Paciej-Gołe˛biowska, Małgorzata Pikala and Irena Maniecka-Bryła. Years of life lost due to malignant neoplasms of the digestive system in Poland in the years 2000–2014. United European Gastroenterology Journal 6(6) 943–951
23. Zenghong Wu1*, Fangnan Xia2 and Rong Lin1* Global burden of cancer and associated risk factors in 204 countries and territories, 1980 2021: a systematic analysis for the GBD 2021. Wu et al. Journal of Hematology & Oncology
24. Bello Yusuf Jamoh, Sani Atta Abubakar, Sani Muhammad Isa. Morbidity and mortality profile of patients seen in medical emergency unit of a Teaching Hospital in Nigeria: A 4‑year audit. Sahel Medical Journal | Published by Wolters Kluwer – Medknow. May 20, 2019, IP: 197.157.252.242
25. Michael J.Thun, John Oliver DeLancey, Melissa M.Center, Ahmedin Jemal and Elizabeth M.Ward. The global burden of cancer: priorities for prevention.A dvance Access publication November 24, 2009. Carcinogenesis vol.31 no.1 pp.100–110, 2010 doi:10.1093/carcin/bgp263
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